I love my Mediclo scrubs and have many sets of both Bottle Fysel and Tree Tencel versions. When brand new the Tencel material is hands down the most comfortable of the two, doesn't pill at all and repels animal hair. However it's greatest downfall is that the color fades dramatically after a single wash on cold water and air dried and yes it does wrinkles a lot. The Fysel Bottle material is more stretchy, resists color fading, and is wrinkle resistant but started noticeably pilling on the pant thighs within two wears and attracts lint. I rather having pilling and lint than noticeable color fading and wrinkles so I'll be buying only the Fysel material from now on.